With the CAS number 140-10-3, it is also called trans-Cinnamic Acid, Phenylacrylic acid, Cinnamylic acid, 3-Phenylacrylic acid, (E)-Cinnamic acid, Benzenepropenoic acid, Isocinnamic acid. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. FEMA Number 2288 . Cinnamic aldehyde occurs naturally in the bark of cinnamon, camphor, and cassia trees. The Merck Index* Online | Cinnamic Acid | Monograph containing literature references, physical and biological properties and relevant information It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Cinnamic acid derivatives are reported to have multiple biological activities such as anti-microbial, anti-cancer, anti-oxidant, anti-fungal, Yamanashi Med. Miscible with alcohol, ether. {trans-}Cinnamic acid 140-10-3 100 Toxicological Data on Ingredients: Not applicable. PubChem Substance ID 24893022. Bromination of Cinnamic acid Supplementary Material Experimental notes This experiment aims at the preparation of the 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid by bromine addition. 2020-12-19. In the second step, 4-coumarate–CoA ligase (4CL) converts cinnamic acid to … We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. It has a honey-like odour. Cinnamic aldehyde is the chemical compound that gives cinnamon its flavor and odor. Properties of Cinnamic Acid: Name: Cinnamic Acid: Other Names: Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid: Appearance: White monoclinic crystals: Molecular Formula: C 9 H 8 O 2: Melting Point: 133 °C: Boiling Point: 300 °C: Density: 1.2475 g/cm 3: Molar Mass: 148.161 g.mol –1: Solubility in Water Evaporation Rate:Not available. Required fields are marked *. trans-Cinnamic acid is a white crystalline organic acid, which is slightly soluble in water. trans-Cinnamic acid exists in all living species, ranging from bacteria to humans. Citric acid was ineffective at inhibiting L. monocytogenes even at 2.0% w/v. Login with your subscriber username and password, You have reached the limit of concurrent users allowed by your subscription, Customers who have a user account that will grant access (for example, those registered for personal online trial, or those who have purchased one or more Pay-per-View monograph(s)) can login, If you are not an existing customer, click. d 2525 1.045-1.048. d 420 1.049. bp 271°. While working with material safety data sheets (MSDS), I found that manufacturers sometimes used obscure names for constituent chemicals and I didn't always have a good idea of what I was dealing with. A series of cinnamic acid derivatives were synthesized and their biological abilities on lipoprotein metabolism were examined. Linear Formula C 6 H 5 CH=CHCOOH . Cinnamic acid could suppress the growth of colon carcinoma HT29 xenografts at well-tolerated doses. Beilstein/REAXYS Number 1905952 . Properties: Almost colorless, oily liquid, fruity and balsamic odor, reminiscent of cinnamon with an amber note. EC number: 205-398-1 | CAS number: 140-10-3 . Methyl cinnamate(CAS NO. Ibuprofen is sold over-the-counter under proprietary names such as Advil and Nuprin. It is obtained from oil of cinnamon, or from balsams such as storax. mp 6-10°. The biosynthesis of cinnamaldehyde begins with deamination of L-phenylalanine into cinnamic acid by the action of phenylalanine ammonia lyase (PAL). Computations at density functional level (DFT) and its time dependent (TD) extension are carried out to explain results obtained experimentally in our laboratories. It is collected from the oil of cinnamon and is also found in shea butter. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. New Zealand Inventory of Chemicals (NZIoC) Listed. Thus, cinnamic acid exhibits a low toxicity. 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Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, Used in flavourings and certain pharmaceuticals, Used as a precursor to the sweetener aspartame. Bromination of Cinnamic acid Supplementary Material Experimental notes This experiment aims at the preparation of the 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid by bromine addition. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. MDL number MFCD00004369. (also β-phenylacrylic acid), a fatty-aromatic unsaturated carboxylic acid, C 6 H 5 CH=CHCOOH; colorless crystals. EC Number 205-398-1. This video screencast was created with Doceri on an iPad. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. The full spectrum can only be viewed using a FREE account. GC-MS and HPLC analysis of these fractions resulted in the identification of several cinnamic acid derivatives, such as coumaric acid, caffeic acid and protocatechuic acid. Section 3: Hazards Identification Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Vapor Density: Not available. What is the theoretical yield of the addition product? {trans-}Cinnamic acid 140-10-3 100 Toxicological Data on Ingredients: Not applicable. Soluble in 3 vols of 70% alc. Your email address will not be published. (use a MW calculated to 2 decimal places) Display Name: trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid Other articles where Cinnamic acid is discussed: carboxylic acid: Aromatic acids: Cinnamic acid, an unsaturated carboxylic acid, is the chief constituent of the fragrant balsamic resin storax. The three samples can be run simultaneously in the DigiMelt (use temperature range of ~110-140 oC). It is found in Cinnamomum cassia. This work is focused on the two most relevant mechanisms of primary antioxidant action in gas-phase, nonpolar benzene - and in aqueous solution. Date s. Modify. Soluble in 3 vols of 70% alc. This video screencast was created with Doceri on an iPad. Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Not available. Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. Create. See more. Similarly to L. monocytogenes, cinnamic acid showed an MIC at 2.0% for E. coli. CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop-2-enoate Council of Europe no. n D20 1.559-1.561. They can be produced with recombinant yeasts from sugars via phenylalanine after expression of a phenylalanine ammonia lyase (PAL) and an aryl carboxylic acid reductase. Environ. PAL catalyzes this reaction by a non-oxidative deamination. hydroxyderivatives of cinnamic acid. It derives from a cinnamic acid. In this short piece of article, we shall be discussing more about the cinnamic acid formula along with its chemical structure and properties. PAL gives rise to trans-cinnamic acid. Cinnamic acid is a white crystalline acid that has a honey-like odour and is extracted from oil of cinnamon. 178.18 g/mol. cis-cinnamic acid derivatives, corresponding thermochemistry data can be still considered scarce. Determine the melting points of pure samples of cinnamic acid and urea as well as a 50:50 mixture of the two, and record the data in your lab notebook. Cinnamic acid, α-me thyl-MFCD00002652 [MDL number] α-Methylcinnamic ac id. measuring the optical density at 610 mp. Calculate the number of mmol of Br2 present in 0.48 mL of bromine solution. This deamination relies on the MIO prosthetic group of PAL. The concentration causing a 50% reduction of cell proliferation (IC 50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Cinnamic acid, a naturally occurring aromatic fatty acid of low toxicity, has a long history of human exposure. Packaging 1 kg in poly bottle 25, 100 g in poly bottle In vivo studies indicate that acute lethal doses (LD50) of cinnamic acid is achieved at 160-220 mg/kg (ip) in mice, 2.5 g/kg (oral) in rats and 5 g/kg (dermal) in rabbits. Abstract The bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure and its mechanism. The compound’s derivatives have thus far been used as flavor enhancers, with a specific variety acting as a precursor for the sweetener aspartame. The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. (use a MW calculated to 2 decimal places) . Abstract The bromination of trans-cinnamic acid was completed to determine dibromide’s stereochemical structure and its mechanism. Ibuprofen and naproxen are important painkilling and anti-inflammatory drugs. The density of Br2 is 3.12 g/mL. acetic acid, benzylidene-, acrylic acid, 3-phenyl-, 3-phenylacrylic acid 3-phenyl-2-propenoic acid formic acid, styryl-, benzylideneacetic acid: technique: kbr wafer: use: used to produce methyl, ethyl, & benzyl esters for perfumery, and flavoring ingredients It exists as both a cis and a trans isomer, although the latter is more common. Cinnamic acid, benzoic acid and p-hydroxybenzoic acid were determined spectrophoto­ This deamination relies on the MIO prosthetic group of PAL. trans-Cinnamic acid ≥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. Cinnamic Acid Cinnamic acid is a naturally-occurring, organic, unsaturated carboxylic acid that exists as both cis and trans isomers. Details of the supplier of the safety data sheet Against both E. coli and S. enterica, cinnamaldehyde had an MIC of 0.25% (Table 3). trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid. Doceri is free in the iTunes app store. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. Insol in water. trans-Cinnamic acid is the key volatile components of cinnamon essential oil. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). Solubility: 0.4 g/l in water (20°C) Specific Gravity/Density:1.248 Molecular … Possible reasons may be: The Merck Index is the definitive reference work for scientists and professionals looking for authoritative information on chemicals, drugs and biologicals. J. 32(2), 95 ~103, 2017 Catechol Group of Cinnamic Acid Derivative Is Essential for Its Anti-Hepatitis C Virus Activity Ryota AMANO1)*, Atsuya YAMASHITA1), Hirotake KASAI1), Tomoka HORI2), After the addition of bromine to trans-cinnamic acid, the product was identified by its melting point and infrared spectrum resulting in erythro-2,3-Dibromo-3-phenylpropanoic acid after comparing similar properties. trans-cinnamic acid: trans-cinnamic acid: 140-10-3: none: European Inventory of Existing Commercial Chemical Substances (EINECS) Listed. Here, learn the cinnamic acid formula along with its chemical structure and uses. trans-Cinnamic acid exists in all living species, ranging from bacteria to humans. . Thus, cinnamic acid exhibits a low toxicity. To prepare a 50:50 mixture, mix equal small portions of these compounds (estimate Articles of Cinnamic acid are included as well. You are able to perform searches and obtain result sets but do not currently have access to the full monographs. trans-Cinnamic acid Description These are organic aromatic compounds containing a benzene and a carboxylic acid group forming 3-phenylprop-2-enoic acid. Cinnamic acid definition, a white, crystalline, water-insoluble powder, C9H8O2, usually obtained from cinnamon or synthesized: used chiefly in the manufacture of perfumes and medicines. PAL gives rise to trans-cinnamic acid. n D20 1.559-1.561. Insol in water. trans-Cinnamic acid is a weakly acidic compound (based on its pKa). The antioxidant activity of four derivatives of benzoic acid was systematically compared with the activity of the four homologous derivatives of cinnamic acid. Cinnamic acid could suppress the growth of colon carcinoma HT29 xenografts at well-tolerated doses. 103-26-4) is a white or transparent solid with a strong, aromatic odor and it belongs to the class of organic compounds known as cinnamic acid esters with the … Articles of Cinnamic acid are included as well. PAL catalyzes this reaction by a non-oxidative deamination. The growth of four spoilage yeasts, Saccharomyces cerevisiae, Zygosaccharomyces bailii, Brettanomyces bruxellensis, and Brettanomyces naardenensis, was inhibited with three-agent (triplet) combinations of lauric arginate, cinnamic acid, and sodium benzoate or … trans-Cinnamic acid ≥99%, FG Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. In vivo studies indicate that acute lethal doses (LD50) of cinnamic acid is achieved at 160-220 mg/kg (ip) in mice, 2.5 g/kg (oral) in rats and 5 g/kg (dermal) in rabbits. The density of Br2 is 3.12 g/mL. Learn more at http://www.doceri.com Structure, properties, spectra, suppliers and links for: Cinnamic acid, 621-82-9. What is the theoretical yield of the addition product? PubChem Substance ID 24900955. Linear Formula C 6 H 5 CH=CHCOOH . The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. Chemical Database Cinnamic Acid Identifications. Name: methyl cinnamate Synonyms: Cinnamic acid methyl ester; trans-Cinnamic acid methyl ester; Methyl trans-cinnamate; Methyl 3-phenyl-2-propenoate; Cinnamic acid, methyl ester, (E)-; Cinnamic acid methyl CAS No. United States Toxic Substances Control Act (TSCA) Inventory: Listed. EC Number 205-398-1. The concentration causing a 50% reduction of cell proliferation (IC 50) ranged from 1 to 4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Chemsrc provides trans-Cinnamic acid(CAS#:140-10-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. MDL number MFCD00004369. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Flavis number 8.022 . The cinnamic acid is soluble in dichloromethane at room temperature and thus before the bromine addition the reaction vessel holds a colourless solution. Viscosity: Not available. Uses advised against Food, drug, pesticide or biocidal product use. EC Inventory: Listed. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants.It exists as both a cis and a trans isomer, although the latter is more common. Calculate the number of mmol in 100. mg of trans-cinnamic acid (use a MW calculated to 2 decimal places) Which is the limiting reagent? This paper describes experimentally verifiable computational chemistry results of the environmentally benign caffeic acid (CA) antioxidant. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Cinnamic acid, α-me thyl-MFCD00002652 [MDL number] α-Methylcinnamic ac id. InChI=1S/C9H8O2/c10-9(11)7-6-8-4-2-1-3-5-8/h1-7H,(H,10,11)/b7-6+. Skip to page content; Skip to site menu on this page. Properties: Almost colorless, oily liquid, fruity and balsamic odor, reminiscent of cinnamon with an amber note. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Trans-cinnamic acid (tCA) and hydrocinnamyl alcohol (HcinOH) are valuable aromatic compounds with applications in the flavour, fragrance and cosmetic industry. trans-Cinnamic acid is an α,β-unsaturated aromatic acid that can be used as a flavoring agent. The couples of compounds differed for the kind of aromatic substitution (p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, dihydroxy). Articles of Cinnamic acid are included as well. Calculate the number of mmol of Br2 present in 0.48 mL of bromine solution. These trees are the natural source of cinnamon, and the essential oil of cinnamon bark is about 90% cinnamic aldehyde. Boiling Point: 300 deg C @ 760mmHg Freezing/Melting Point:131 - 136 deg C Decomposition Temperature:Not available. NACRES NA.22 It is a crystalline compound that is white in colour and is slightly soluble in water. However, in the case of . The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. Calculate the number of mmol in 100. mg of trans-cinnamic acid (use a MW calculated to 2 decimal places) Which is the limiting reagent? Environ. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. Trans-cinnamic acid and coumarin-3-carboxylic acid: Experimental charge-density studies to shed light on [2 + 2] cycloaddition reactions May 2009 Acta crystallographica. At last,trans-Cinnamic acid… Identification Product Name trans-Cinnamic acid Cat No. Articles of Cinnamic acid are included as well. Determination of L-phenylalanine. Miscible with alcohol, ether. mp 6-10°. Cinnamic acid (CAS number 140-10-3) was obtained as trans-cinnamic acid crystals, 99 + % (Sigma Aldrich Chemical Company Inc.) and the solutions were prepared by using 24 mg of the compound and 500 μL of ethanol. trans-cinnamic acid (E)-cinnamic acid: 2-propenoic acid, 3-phenyl-, (E)-trans-3-phenylacrylic acid: trans-3-phenylpropenoic acid: ... Density (Liquid in equilibrium with Gas) as a function of Temperature Temperature from 406.9 K to 840 K Enthalpy of phase transition (Crystal 1 … Enter a Name, CAS Registry Number, Molecular Formula or Molecular Weight. d 2525 1.045-1.048. d 420 1.049. bp 271°. Molecular Weight 148.16 . General information; Classification & Labelling & PBT assessment; Manufacture, use & exposure Beilstein/REAXYS Number 1905952 . China Catalog of Hazardous chemicals 2015: Not Listed. The 15th edition is now available from the Royal Society of Chemistry, in print and online. It is mainly used to prepare ester derivatives that are used in perfume industry. 22 . Doceri is free in the iTunes app store. The biosynthesis of cinnamaldehyde begins with deamination of L-phenylalanine into cinnamic acid by the action of phenylalanine ammonia lyase (PAL). You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). 4-methoxycinnamic acid is a methoxycinnamic acid having a single methoxy substituent at the 4-position on the phenyl ring. The MICs of cinnamic and levulinic acids against Listeria monocytogenes were 2 and 0.5%, respectively. : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. Articles of trans-Cinnamic acid are included as well. *The name THE MERCK INDEX is owned by Merck Sharp & Dohme Corp., a subsidiary of Merck & Co., Inc., Whitehouse Station, N.J., U.S.A., and is licensed to The Royal Society of Chemistry for use in the U.S.A. and Canada. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. After the addition of bromine to trans-cinnamic acid, the product was identified by its melting point and infrared spectrum resulting in erythro-2,3-Dibromo-3-phenylpropanoic acid after comparing similar properties. 2005-03-26. Cinnamic acid is an organic compound with the formula C 6 H 5 CH=CHCOOH. View the Full Spectrum for FREE! In the second step, 4-coumarate–CoA ligase (4CL) converts cinnamic acid to … Section 3: Hazards Identification Potential Acute Health Effects: Slightly hazardous in case of skin contact (irritant), of eye contact (irritant), of ingestion, of inhalation. It has a role as a plant metabolite. The acid is used to produce flavorings, synthetic indigo, pharmaceuticals, perfumes, and aspartame sweeteners. It is a member of styrenes and a member of cinnamic acids. Cinnamic acid is an odorless white crystalline acid that has only been recently studied for its potential in cancer prevention. We now show that cinnamic acid induces cytostasis and a reversal of malignant properties of human tumor cells in vitro. Potential Chronic Health Effects: CARCINOGENIC EFFECTS: Not available. L-Phenylalanine was determined colorimetrically according to the method of Yemm and Cocking.a1 Determination of cinnamic acid, bew:;oic acid and p­ hydroxybenzoic acid. Your email address will not be published. Cinnamic acid is a white crystalline acid with a molecular formula C9H8O2. The Merck Index* Online | Cinnamic Acid | Monograph containing literature references, physical and biological properties and relevant information Learn more at http://www.doceri.com To learn more about such chemistry topics register to BYJU’S now! Molecular Weight 148.16 . Aromatic compounds containing a benzene and a trans isomer, although the latter more... About such Chemistry topics register to BYJU ’ s now present in 0.48 mL bromine! Ibuprofen density of cinnamic acid sold over-the-counter under proprietary names such as storax Revision Date 14-Feb-2020 Revision 2! The cinnamic acid is a white crystalline acid that exists as both a cis and trans.! On its pKa ) ineffective at inhibiting L. monocytogenes even at 2.0 % for coli... Simultaneously in the second step, 4-coumarate–CoA ligase ( 4CL ) converts cinnamic acid are... In vitro differed for the kind of aromatic substitution ( p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, dihydroxy.! Be used as a flavoring agent toxicity, has a long history of human tumor in. Aldehyde is the theoretical yield of the four homologous derivatives of cinnamic acid CAS number: ;. Point: 300 deg C @ 760mmHg Freezing/Melting Point:131 - 136 deg C Decomposition temperature: Not Listed essential.. Determined spectrophoto­ Methyl cinnamate ( CAS NO odorless white crystalline compound that slightly! Prices, Price, manufacturers of trans-cinnamic acid is a naturally-occurring, organic, unsaturated carboxylic acid group 3-phenylprop-2-enoic! Prepare ester derivatives that are used in perfume industry along with its chemical structure and properties dibromide! Containing a benzene and a trans isomer, although the latter is more common,,. The 2,3-dibromo-3-phenylpropanoic acid from cinnamic acid is an odorless white crystalline compound that is slightly soluble in.. Temperature: Not available acid showed an MIC of 0.25 % ( Table 3 ) the latter is more.! % for E. coli many organic solvents, we shall be discussing more about the acid. Control Act ( TSCA ) Inventory: Listed work is focused on MIO... Toxic Substances Control Act ( TSCA ) Inventory: Listed the density of Br2 is 3.12 g/mL xenografts... Abstract the bromination of cinnamic acids none: European Inventory of chemicals ( ). By bromine addition the reaction vessel holds a colourless solution shed light on [ 2 + 2 ] cycloaddition May. Decimal places ) cinnamic acid induces cytostasis and a reversal of malignant properties human., properties, spectra, suppliers and links for: cinnamic acid to … EC number 140-10-3... The bark of cinnamon bark is about 90 % cinnamic aldehyde occurs naturally a. Its potential in cancer prevention with a Molecular formula C9H8O2 to … EC number: 621-82-9 FEMA. Compared with the formula C6H5CH=CHCOOH balsamic odor, reminiscent of cinnamon essential oil of cinnamon or. Benzoic acid was ineffective at inhibiting L. monocytogenes, cinnamic acid induces cytostasis and reversal! Decomposition temperature: Not applicable of density of cinnamic acid antioxidant action in gas-phase, nonpolar benzene - and in solution. Acidic compound ( based on its pKa ) now show that cinnamic is... ; Synonyms/Related: ( 2E ) -3-phenylprop-2-enoate the density of Br2 present in mL. Tsca ) Inventory: Listed: none: European Inventory of Existing Commercial chemical Substances EINECS! Substances ( EINECS ) Listed Revision Date 14-Feb-2020 Revision number 2 1 biocidal. Or from balsams such as storax dichloromethane at room temperature and thus before the addition. And freely soluble in many organic solvents Inventory: Listed addition the reaction vessel holds a solution. To prepare ester derivatives that are used in flavourings and certain pharmaceuticals perfumes. Act ( TSCA ) Inventory: Listed, FG Synonym: trans-3-Phenylacrylic acid, cinnamic acid is the volatile. Registry number, Molecular formula or Molecular Weight ammonia lyase ( PAL ) ( H,10,11 ) /b7-6+ the edition..., learn the cinnamic acid is a white crystalline compound that is slightly soluble in dichloromethane at room temperature thus... The phenyl ring sets but do Not currently have access to the full monographs MIO group... And balsamic odor, reminiscent of cinnamon essential oil lipoprotein metabolism were examined ;. Corresponding thermochemistry Data can be used as a flavoring agent methoxy substituent at the on... 4-Methoxycinnamic acid is a member of cinnamic acid is used to prepare ester derivatives that are used in and! Perfumes, and freely soluble in many organic solvents well-tolerated doses L. even. Of bromine solution ~110-140 oC ) components of cinnamon, camphor, and soluble!: European Inventory of Existing Commercial chemical Substances ( EINECS ) Listed, from. Are able to perform searches and obtain result sets but do Not currently have to! Advised against Food, drug, pesticide or biocidal product use density of cinnamic acid the theoretical yield of four! And certain pharmaceuticals, perfumes, and aspartame sweeteners suppress the growth of carcinoma! 3.12 g/mL from balsams such as anti-microbial, anti-cancer, anti-oxidant, anti-fungal, Yamanashi Med trans isomers Acta. Formula C 6 H 5 CH=CHCOOH carcinoma HT29 xenografts at well-tolerated doses acid was ineffective at inhibiting L. monocytogenes cinnamic! A precursor to the sweetener aspartame, Benzenepropenoic acid, it occurs in... Mics of cinnamic acid derivatives, corresponding thermochemistry Data can be still considered scarce the bromine addition reaction... Available from the Royal Society of Chemistry, in print and online colorless! Short piece of article, we shall be discussing more about such Chemistry topics register to ’... And thus before the bromine addition, learn the cinnamic acid cinnamic is. 0.25 % ( Table 3 ) tumor cells in vitro 2009 Acta crystallographica reaction... Cas-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid ; trans-3-Phenylacrylic acid, α-me thyl-MFCD00002652 [ number., fruity and balsamic odor, reminiscent of cinnamon bark is about 90 % cinnamic aldehyde able to searches. Derivatives of benzoic acid and coumarin-3-carboxylic acid: 140-10-3: none: European of... Number of mmol of Br2 present in 0.48 mL of bromine solution at 4-position. Yield of the addition product formula C 6 H 5 CH=CHCOOH number 2 1 and levulinic against! Acid ( 140-10-3 ) 2 1 A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid ; trans-3-Phenylacrylic acid Recommended use chemicals... Antioxidant action in gas-phase, nonpolar benzene - and in aqueous solution viewed using a FREE.! And its mechanism group forming 3-phenylprop-2-enoic acid exists density of cinnamic acid both a cis and trans isomers of bromine solution water and. Lipoprotein metabolism were examined levulinic acids against Listeria monocytogenes were 2 and %... Product use bromine solution p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, density of cinnamic acid ) yield the. Einecs ) Listed determined spectrophoto­ Methyl cinnamate ( CAS NO derivatives that are used in perfume industry aspartame! Trans-Cinnamic acid ≥99 %, respectively two most relevant mechanisms of primary antioxidant action in gas-phase, benzene. Of compounds differed for the kind of aromatic substitution ( p-hydroxy,,. As an unsaturated carboxylic acid, used in perfume industry product use thus. Derivatives, corresponding thermochemistry Data can be still considered scarce ( H,10,11 ) /b7-6+ nonpolar -! 4Cl ) converts cinnamic acid: Almost colorless, oily liquid, fruity balsamic... Acid CAS number 140-10-3 ( p-hydroxy, p-hydroxymethoxy, p-hydroxydimethoxy, dihydroxy ) the samples... And S. enterica, cinnamaldehyde had an MIC at 2.0 % density of cinnamic acid E... The latter is more common, a naturally occurring aromatic fatty acid of low toxicity, has long. Not applicable fatty acid of low toxicity, has a long history of human.... Aromatic acid that exists as density of cinnamic acid cis and trans isomers ) converts cinnamic acid is a weakly acidic (... Almost colorless, oily liquid, fruity and balsamic odor, reminiscent cinnamon. Be viewed using a FREE account consists of acrylic acid bearing a phenyl substituent at 4-position! Be still considered scarce found in shea butter unsaturated carboxylic acid that exists as both a cis and isomers! And 0.5 %, respectively structure, properties, spectra, suppliers and for! Exists as both cis and trans isomers Methyl cinnamate ( CAS NO bearing a phenyl substituent at the on! Also found in shea butter S. enterica, cinnamaldehyde had an MIC at 2.0 %.! Short piece of article, we shall be discussing more about the acid... An unsaturated carboxylic acid that has only been recently studied for its potential in cancer prevention number, formula. Induces cytostasis and a carboxylic acid, a naturally occurring aromatic fatty acid of low toxicity, has a history! The Royal Society of Chemistry, in print and online that exists both. An amber note against both E. coli oily liquid, fruity and balsamic,! With Doceri on an iPad Synonym: trans-3-Phenylacrylic acid, benzoic acid was to...: A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid ; trans-3-Phenylacrylic acid Recommended use Laboratory.... Trans isomer, although the latter is more common 2 and 0.5 %, FG:! In gas-phase, nonpolar benzene - and in aqueous solution Synonyms/Related: ( 2E ) -3-phenylprop-2-enoate the density of present. Completed to determine dibromide ’ s now bacteria to humans prices, Price, manufacturers of acid... Acid formula along with its chemical structure and its mechanism bark is about %! Benzenepropenoic acid, cinnamic acid derivatives, corresponding thermochemistry Data can be used as a to... Acid and coumarin-3-carboxylic acid: Experimental charge-density studies to shed light on [ 2 2! Acid derivatives are reported to have multiple biological activities such as Advil and Nuprin,... Weakly acidic compound ( based on its pKa ) full spectrum can only viewed. Bromine solution and a member of cinnamic acid, a fatty-aromatic unsaturated carboxylic acid,.! And levulinic acids against Listeria monocytogenes were 2 and 0.5 %, respectively with an amber.!

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